The Role of IL-6 and TMEM100 in Lumbar Discogenic Pain and the Mechanism of the Glycine-Serine-Threonine Metabolic Axis: A Metabolomic and Molecular Biology Study.

Zhaoyang GuoYuanye MaYaqing WangHongfei XiangShang-You YangZhu GuoRonghuan WangWujun ChenDongming XingBohua ChenHao TaoXiaolin Wu

Published in: Journal of pain research (2023)

The change of TMEM100 expression mediated by il-6 is related to the Gly-Ser-Thr metabolic axis and plays an important role in the relief of discogenic pain.

Keyphrases

chronic pain
pain management
neuropathic pain
poor prognosis
protein kinase
spinal cord