Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway.

Chen Yao Jie Sun Wanxin Luo Hao Chen Tianhao Chen Cao Chen Bo Zhang Yafeng Zhang

Published in: Bone & joint research (2024)

Reduced expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenic differentiation and accelerates age-related bone loss via PTEN/PI3K/AKT pathway.

Keyphrases

bone loss
mesenchymal stem cells
poor prognosis
stem cells
cell proliferation
pi k akt
binding protein
long non coding rna