In Vivo 18 F-APN-1607 Tau Positron Emission Tomography Imaging in MAPT Mutations: Cross-Sectional and Longitudinal Findings.

Xin-Yue ZhouJia-Ying LuFeng-Tao LiuPing WuJue ZhaoZi-Zhao JuYi-Lin TangQing-Yi ShiHua-Mei LinJian-Jun WuTzu-Chen YenChuan-Tao ZuoYi-Min SunJian Wang

Published in: Movement disorders : official journal of the Movement Disorder Society (2021)

Our data represent a promising step in understanding the usefulness of 18 F-APN-1607 PET/CT imaging for detecting tau accumulation in MAPT mutation carriers. Our preliminary follow-up data also suggest the potential value of 18 F-APN-1607 PET/CT for monitoring the longitudinal trajectories of frontotemporal lobar degeneration caused by MAPT mutations. © 2021 International Parkinson and Movement Disorder Society.

Keyphrases

pet ct
positron emission tomography
cross sectional
high resolution
computed tomography
electronic health record
big data
cerebrospinal fluid
pet imaging
depressive symptoms
machine learning
mass spectrometry
human health
photodynamic therapy