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Evaluation of the efficacy and safety of toceranib phosphate in cats with macroscopic mammary adenocarcinoma.

Isabel Del Portillo MiguelLaura BlackwoodElisa MaiquesIgnacio Pérez RogerEnric Poch JiménezJuan Borrego
Published in: Journal of feline medicine and surgery (2024)
Toceranib phosphate showed clinical benefit and a good safety profile in advanced or recurrent FMTs, offering a new alternative in the treatment of this disease; however, further prospective and randomised studies are required to further assess its efficacy. Interestingly, one cat developed distant metastases while the primary tumour showed partial response, suggesting that primary tumour and metastatic disease may not sustain the same sensitivity to toceranib.
Keyphrases
  • squamous cell carcinoma
  • clinical trial
  • small cell lung cancer
  • open label
  • lymph node
  • randomized controlled trial
  • study protocol
  • locally advanced
  • placebo controlled