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Aberrant expression of N-glycolyl GM3 ganglioside is associated with the aggressive biological behavior of human sarcomas.

Daniel F Pilco-JanetaMyriam De la Cruz PueblaJorge SorianoMarta OsorioIraida CaballeroAdanays Calvo PérezLaynes SavonNatalia CremadesRancés BlancoAdriana Carr
Published in: BMC cancer (2019)
The present research suggests the evaluation of NeuGcGM3 expression as a complementary prognostic factor in sarcoma, although our results need to be validated in a larger series and prospective studies. Moreover, our results could support the use of this molecule as a target for immunotherapy.
Keyphrases
  • prognostic factors
  • poor prognosis
  • endothelial cells
  • binding protein
  • long non coding rna
  • high grade