Polygenic risk for alcohol misuse is moderated by romantic partnerships.

Peter B BarrSally I-Chun KuoFazil Aliev Antti LatvalaRichard VikenRichard J Rose Jaakko A Kaprio Jessica E Salvatore Danielle M Dick

Published in: Addiction (Abingdon, England) (2019)

Being in a romantic relationship reduced the association between genetic predisposition and drinking, high-risk drinking and alcohol problems. However, for high-risk drinking the protective effect was limited to males, mapping onto earlier findings suggesting that males benefit more from romantic partnerships.

Keyphrases

alcohol consumption
mental health
global health
high resolution
chronic pain
genome wide
high density