MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer.

Haichang LiPei-Hui LinPranav GuptaXiangguang LiSerena Li ZhaoXinyu ZhouZhongguang LiShengcai WeiLi XuRenzhi HanJing LuTao TanDong-Hua YangZhe-Sheng ChenTimothy M PawlikRobert E MerrittJianjie Ma

Published in: Molecular cancer (2021)

Overall, these findings support the notion that MG53 functions as a tumor suppressor by targeting G3BP2/SG activity in NSCLCs.

Keyphrases

signaling pathway
poor prognosis
long non coding rna