Asprosin contributes to pathogenesis of obesity by adipocyte mitophagy induction to inhibit white adipose browning in mice.

Sheng Chen Wanwan Yuan Qianqian Huang Qianqian Huang Chaowen WangWenjing ZengLi Wang Yijun Huang Yeyi Liu Yan Wang Qiren Huang

Published in: International journal of obesity (2005) (2024)

These data demonstrate that ASP deletion can facilitate the browning and inhibit mitophagy in WAT. The findings will lay an experimental foundation for the development of new drugs targeting ASP and the clinical treatment of metabolic diseases related to obesity.

Keyphrases

high fat diet induced
insulin resistance
adipose tissue
metabolic syndrome
skeletal muscle
type diabetes
cancer therapy
drug induced
fatty acid
weight gain
deep learning
physical activity
machine learning
data analysis
drug delivery