Login / Signup

HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.

Na JiangHao ZhaoYachun HanLi LiShan XiongLingfeng ZengYing XiaoLing WeiXiaofen XiongPeng GaoMing YangYu LiuLin Sun
Published in: Cell proliferation (2020)
These data revealed that HIF-1α exerted a protective effect against tubular injury in DN, which could be mediated via modulation of mitochondrial dynamics through HO-1 upregulation.
Keyphrases
  • diabetic nephropathy
  • oxidative stress
  • endothelial cells
  • high glucose
  • pi k akt
  • cell proliferation
  • poor prognosis
  • electronic health record
  • signaling pathway
  • mouse model
  • big data
  • machine learning