Protective effects of L-carnitine on X irradiation-induced uterus injury via antioxidant and anti-inflammatory pathways.
Serkan KaracetinMeryem AkpolatZehra Safi OzAyse Ceylan HamamciogluPublished in: International journal of radiation biology (2023)
Our findings showed that L-carnitine has a positive effect on radiation-induced uterine damage. L-carnitine may be a potential safe radio protective agent during radiotherapy for pelvic cancer provided the tumor is not protected from radiation damage to the same extent as the normal tissue is. However, prospective clinical trial studies are necessary to understand its efficacy.
Keyphrases
- radiation induced
- anti inflammatory
- oxidative stress
- clinical trial
- radiation therapy
- diabetic rats
- papillary thyroid
- high glucose
- squamous cell
- rectal cancer
- early stage
- randomized controlled trial
- study protocol
- phase ii
- locally advanced
- endothelial cells
- double blind
- young adults
- climate change
- childhood cancer
- lymph node metastasis