Current Management of Acute and Posttraumatic Critical Bone Defects.
Mitchell BernsteinMilton T M LittleGeoffrey S MarecekPublished in: Journal of orthopaedic trauma (2024)
Limb reconstruction in patients with critical-sized bone defects remains a challenge due to the availability of various technically demanding treatment options and a lack of standardized decision algorithms. Although no consensus exists, it is apparent from the literature that the combination of patient, surgeon, and institutional collaborations is effective in providing the most efficient care pathway for these patients. Success relies on choosing a particular surgical approach that manages infection, soft tissue defects, stability, and alignment. Recent systematic reviews demonstrate high success rates with the following management options: Ilizarov bone transport, Masquelet (induced membrane) technique, cancellous bone grafting, and vascularized bone grafts.
Keyphrases
- soft tissue
- bone mineral density
- bone loss
- systematic review
- healthcare
- end stage renal disease
- machine learning
- newly diagnosed
- postmenopausal women
- chronic kidney disease
- drug induced
- palliative care
- liver failure
- randomized controlled trial
- computed tomography
- prognostic factors
- deep learning
- quality improvement
- extracorporeal membrane oxygenation
- endothelial cells
- decision making
- minimally invasive