Metabolomic analysis of serum samples from a clinical study on ipragliflozin and metformin treatment in Japanese patients with type 2 diabetes: Exploring human metabolites associated with visceral fat reduction.

Ayano Tsukagoshi-YamaguchiMasaya KoshizakaRyoichi IshibashiKo IshikawaTakahiro IshikawaMayumi ShojiShintaro IdeKana IdeYusuke BabaRyo TerayamaAkiko HattoriMinoru TakemotoYasuo OuchiYoshiro MaezawaKoutaro Yokotenull null

Published in: Pharmacotherapy (2023)

Metabolites that may affect visceral fat reduction were detected in the ipragliflozin group. Studies are required to further elucidate the underlying mechanisms.

Keyphrases

adipose tissue
ms ms
insulin resistance
endothelial cells
induced pluripotent stem cells
metabolic syndrome
skeletal muscle
pluripotent stem cells
case control