Significant reduction in heart rate variability is a feature of acute decompensation of cirrhosis and predicts 90-day mortality.
Christian JansenDevnandan Amor ChatterjeeKaren Louise ThomsenBaravan Al-KassouRohit SawhneyHelen JonesAngela Gallego-LeonJennifer LehmannAlessandra PohlmannGeorg NickenigChristian P StrassburgRené AndriéRajiv JalanMarkus LinhartJonel TrebickaRajeshwar Prosad MookerjeePublished in: Alimentary pharmacology & therapeutics (2019)
This study demonstrates that remote wireless HRV monitoring identifies cirrhosis patients at high risk of developing ACLF and death, and suggests such monitoring might guide the need for early intervention in such patients. Clinical Trial number: NIHR clinical research network CPMS ID 4949.
Keyphrases
- heart rate variability
- clinical trial
- end stage renal disease
- heart rate
- ejection fraction
- chronic kidney disease
- randomized controlled trial
- newly diagnosed
- liver failure
- machine learning
- prognostic factors
- genome wide
- blood pressure
- deep learning
- study protocol
- gene expression
- dna methylation
- coronary artery disease
- hepatitis b virus