Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway.

Da TangGuang FuWenbo LiPing SunPatricia A LoughranMeihong DengMelanie J ScottTimothy R Billiar

Published in: Molecular medicine (Cambridge, Mass.) (2021)

MaR1 protects the liver against hepatic I/R injury via an ALXR/Akt signaling pathway. MaR1 may represent a novel therapeutic agent to mitigate the detrimental effects of I/R-induced liver injury.

Keyphrases

signaling pathway
ischemia reperfusion injury
pi k akt
induced apoptosis
epithelial mesenchymal transition
cell proliferation
oxidative stress