Timothy R Billiar (Timothy Billiar)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Topics

Trauma Patients

Inflammatory Response

Top Venues

Cell death & disease

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Haoran Hu, Xinjun Wang, Site Feng, Zhongli Xu, Jing Liu, Elisa Heidrich-O'Hare, Yanshuo Chen, Molin Yue, Lang Zeng, Ziqi Rong, Tianmeng Chen, Timothy R Billiar, Ying Ding, Heng Huang, Richard H Duerr, Wei Chen
A unified model-based framework for doublet or multiplet detection in single-cell multiomics data. Nature communications 15 (1) (2024)
Haoran Hu, Xinjun Wang, Site Feng, Zhongli Xu, Jing Liu, Elisa Heidrich-O'Hare, Yanshuo Chen, Molin Yue, Lang Zeng, Ziqi Rong, Tianmeng Chen, Timothy R Billiar, Ying Ding, Heng Huang, Richard H Duerr, Wei Chen
A unified model-based framework for doublet or multiplet detection in single-cell multiomics data. Nature communications 15 (1) (2024)
Haoran Hu, Xinjun Wang, Site Feng, Zhongli Xu, Jing Liu, Elisa Heidrich-O'Hare, Yanshuo Chen, Molin Yue, Lang Zeng, Ziqi Rong, Tianmeng Chen, Timothy R Billiar, Ying Ding, Heng Huang, Richard H Duerr, Wei Chen
A unified model-based framework for doublet or multiplet detection in single-cell multiomics data. Nature communications 15 (1) (2024)
Shimena Li, Hamed Moheimani, Brachman Herzig, Michael Kail, Neha Krishnamoorthi, Junru Wu, Sultan Abdelhamid, Jacob Scioscia, Eunseo Sung, Anna Rosengart, Jillian Bonaroti, Par I Johansson, Jakob Stensballe, Matthew Neal, Jishnu Das, Upendra Kar, Jason Sperry, Timothy R Billiar
High Dimensional Proteomics Identifies Organ Injury Patterns Associated with Outcomes in Human Trauma. The journal of trauma and acute care surgery (2023)
Robert Y S Cheng, Lisa A Ridnour, Adelaide L Wink, Ana L Gonzalez, Elise L Femino, Helene Rittscher, Veena Somasundaram, William F Heinz, Leandro Coutinho, M Cristina Rangel, Elijah F Edmondson, Donna Butcher, Robert J Kinders, Xiaoxian Li, Stephen T C Wong, Daniel W McVicar, Stephen K Anderson, Milind Pore, Stephen M Hewitt, Timothy R Billiar, Sharon A Glynn, Jenny C Chang, Stephen J Lockett, Stefan Ambs, David A Wink
Interferon-gamma is quintessential for NOS2 and COX2 expression in ER - breast tumors that lead to poor outcome. Cell death & disease 14 (5) (2023)
Robert Y S Cheng, Lisa A Ridnour, Adelaide L Wink, Ana L Gonzalez, Elise L Femino, Helene Rittscher, Veena Somasundaram, William F Heinz, Leandro Coutinho, M Cristina Rangel, Elijah F Edmondson, Donna Butcher, Robert J Kinders, Xiaoxian Li, Stephen T C Wong, Daniel W McVicar, Stephen K Anderson, Milind Pore, Stephen M Hewitt, Timothy R Billiar, Sharon A Glynn, Jenny C Chang, Stephen J Lockett, Stefan Ambs, David A Wink
Interferon-gamma is quintessential for NOS2 and COX2 expression in ER - breast tumors that lead to poor outcome. Cell death & disease 14 (5) (2023)
Robert Y S Cheng, Lisa A Ridnour, Adelaide L Wink, Ana L Gonzalez, Elise L Femino, Helene Rittscher, Veena Somasundaram, William F Heinz, Leandro Coutinho, M Cristina Rangel, Elijah F Edmondson, Donna Butcher, Robert J Kinders, Xiaoxian Li, Stephen T C Wong, Daniel W McVicar, Stephen K Anderson, Milind Pore, Stephen M Hewitt, Timothy R Billiar, Sharon A Glynn, Jenny C Chang, Stephen J Lockett, Stefan Ambs, David A Wink
Interferon-gamma is quintessential for NOS2 and COX2 expression in ER - breast tumors that lead to poor outcome. Cell death & disease 14 (5) (2023)
Timothy R Billiar, Beverley J Hunt, Sebastien Bailly
Targeting inflammation in traumatic injury: entering a new era. Intensive care medicine (2023)
Robert Y S Cheng, Lisa A Ridnour, Adelaide L Wink, Ana L Gonzalez, Elise L Femino, Helene Rittscher, Veena Somasundaram, William F Heinz, Leandro Coutinho, M Cristina Rangel, Elijah F Edmondson, Donna Butcher, Robert J Kinders, Xiaoxian Li, Stephen T C Wong, Daniel W McVicar, Stephen K Anderson, Milind Pore, Stephen M Hewitt, Timothy R Billiar, Sharon A Glynn, Jenny C Chang, Stephen J Lockett, Stefan Ambs, David A Wink
Interferon-gamma is quintessential for NOS2 and COX2 expression in ER - breast tumors that lead to poor outcome. Cell death & disease 14 (5) (2023)
Shimena Li, Hamed Moheimani, Brachman Herzig, Michael Kail, Neha Krishnamoorthi, Junru Wu, Sultan Abdelhamid, Jacob Scioscia, Eunseo Sung, Anna Rosengart, Jillian Bonaroti, Par I Johansson, Jakob Stensballe, Matthew Neal, Jishnu Das, Upendra Kar, Jason Sperry, Timothy R Billiar
High Dimensional Proteomics Identifies Organ Injury Patterns Associated with Outcomes in Human Trauma. The journal of trauma and acute care surgery (2023)
Fangfang Yuan, Jizhen Cai, Jianfeng Wu, Yiting Tang, Kai Zhao, Fang Liang, Fanglin Li, Xinyu Yang, Zhihui He, Timothy R Billiar, Haichao Wang, Lei Su, Ben Lu
Z-DNA binding protein 1 promotes heatstroke-induced cell death. Science (New York, N.Y.) 376 (6593) (2022)
Tejaswini P Reddy, Sharon A Glynn, Timothy R Billiar, David A Wink, Jenny C Chang
Targeting Nitric Oxide: Say NO to Metastasis. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Runliu Wu, Jiao Liu, Nian Wang, Ling Zeng, Chunhua Yu, Feng Chen, Haichao Wang, Timothy R Billiar, Jianxin Jiang, Daolin Tang, Rui Kang
Aconitate decarboxylase 1 is a mediator of polymicrobial sepsis. Science translational medicine 14 (659) (2022)
Junru Wu, Anthony Cyr, Danielle S Gruen, Tyler C Lovelace, Panayiotis V Benos, Jishnu Das, Upendra K Kar, Tianmeng Chen, Francis X Guyette, Mark H Yazer, Brian J Daley, Richard S Miller, Brian G Harbrecht, Jeffrey A Claridge, Herb A Phelan, Brian S Zuckerbraun, Matthew D Neal, Pär I Johansson, Jakob Stensballe, Rami A Namas, Yoram Vodovotz, Jason L Sperry, Timothy R Billiar, null null
Lipidomic signatures align with inflammatory patterns and outcomes in critical illness. Nature communications 13 (1) (2022)
Tejaswini P Reddy, Sharon A Glynn, Timothy R Billiar, David A Wink, Jenny C Chang
Targeting Nitric Oxide: Say NO to Metastasis. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Junru Wu, Anthony Cyr, Danielle S Gruen, Tyler Lovelace, Panayiotis V Benos, Tianmeng Chen, Francis Guyette, Mark Yazer, Brian J Daley, Richard Miller, Brian Harbrecht, Jeffrey Claridge, Herb Phelan, Brian Zuckerbraun, Matthew Neal, Pär Johansson, Jakob Stensballe, Rami Namas, Yoram Vodovotz, Jason Sperry, Timothy R Billiar, PAMPer Study Group
Lipidomic Signatures Align with Inflammatory Patterns and Outcomes in Critical Illness. Research square (2021)
Yao Tong, Zhuang Yu, Zhixia Chen, Renlingzi Zhang, Xibing Ding, Xiaohu Yang, Xiaoyin Niu, Mengzhu Li, Lingling Zhang, Timothy R Billiar, Bruce R Pitt, Quan Li
The HIV protease inhibitor Saquinavir attenuates sepsis-induced acute lung injury and promotes M2 macrophage polarization via targeting matrix metalloproteinase-9. Cell death & disease 12 (1) (2021)
Da Tang, Guang Fu, Wenbo Li, Ping Sun, Patricia A Loughran, Meihong Deng, Melanie J Scott, Timothy R Billiar
Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway. Molecular medicine (Cambridge, Mass.) 27 (1) (2021)
Huan Yang, Qiong Zeng, Harold A Silverman, Manojkumar Gunasekaran, Sam J George, Alex Devarajan, Meghan E Addorisio, Jianhua Li, Téa Tsaava, Vivek Shah, Timothy R Billiar, Haichao Wang, Michael Brines, Ulf Andersson, Valentin A Pavlov, Eric H Chang, Sangeeta S Chavan, Kevin J Tracey
HMGB1 released from nociceptors mediates inflammation. Proceedings of the National Academy of Sciences of the United States of America 118 (33) (2021)
Xiangyu Wang, Zhaozheng Li, Yang Bai, Rui Zhang, Ran Meng, Fangping Chen, Haichao Wang, Timothy R Billiar, Xianzhong Xiao, Ben Lu, Yiting Tang
A small molecule binding HMGB1 inhibits caspase-11-mediated lethality in sepsis. Cell death & disease 12 (4) (2021)
Zhengzheng Yan, Haihua Luo, Bingyao Xie, Tian Tian, Shan Li, Zhixia Chen, Jinghua Liu, Xuwen Zhao, Liyong Zhang, Yongqiang Deng, Timothy R Billiar, Yong Jiang
Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis. Nature communications 12 (1) (2021)
Xinfeng Guo, Silvia Liu, Rose Yan, Vy Nguyen, Mazen Zenati, Timothy R Billiar, Qingde Wang
ADAR1 RNA editing regulates endothelial cell functions via the MDA-5 RNA sensing signaling pathway. Life science alliance 5 (3) (2021)
Junke Long, Chenxuan Yang, Yawen Zheng, Patricia Loughran, Guang Fu, Yiming Li, Hong Liao, Melanie J Scott, Daolin Tang, Timothy R Billiar, Meihong Deng
Notch signaling protects CD4 T cells from STING-mediated apoptosis during acute systemic inflammation. Science advances 6 (39) (2020)
Ronghua Wang, David A Geller, David A Wink, Bin Cheng, Timothy R Billiar
NO and hepatocellular cancer. British journal of pharmacology 177 (24) (2019)
Ronghua Wang, Yawen Li, Allan Tsung, Hai Huang, Qiang Du, Muqing Yang, Meihong Deng, Si Xiong, Xiju Wang, Liyong Zhang, David A Geller, Bin Cheng, Timothy R Billiar
iNOS promotes CD24+CD133+ liver cancer stem cell phenotype through a TACE/ADAM17-dependent Notch signaling pathway. Proceedings of the National Academy of Sciences of the United States of America 115 (43) (2018)
Ruben Zamora, Sebastian Korff, Qi Mi, Derek Barclay, Lukas Schimunek, Riccardo Zucca, Xerxes D Arsiwalla, Richard L Simmons, Paul Verschure, Timothy R Billiar, Yoram Vodovotz
A computational analysis of dynamic, multi-organ inflammatory crosstalk induced by endotoxin in mice. PLoS computational biology 14 (11) (2018)
Zhigang Li, Yang Jiao, Erica K Fan, Melanie J Scott, Yuehua Li, Song Li, Timothy R Billiar, Mark A Wilson, Xue-Yin Shi, Jie Fan
Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria. Journal of immunology (Baltimore, Md. : 1950) 199 (9) (2017)
Jing Xu, Jesse Guardado, Rosemary Hoffman, Hui Xu, Rami A Namas, Yoram Vodovotz, Li Xu, Mostafa Ramadan, Joshua Brown, Heth R Turnquist, Timothy R Billiar
IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model. PLoS medicine 14 (7) (2017)
Timothy R Billiar, Yoram Vodovotz
Time for trauma immunology. PLoS medicine 14 (7) (2017)
Othman Abdul-Malak, Yoram Vodovotz, Akram Zaaqoq, Jesse Guardado, Khalid Almahmoud, Jinling Yin, Brian Scott Zuckerbraun, Andrew B Peitzman, Jason Sperry, Timothy R Billiar, Rami A Namas
Elevated Admission Base Deficit Is Associated with a Complex Dynamic Network of Systemic Inflammation Which Drives Clinical Trajectories in Blunt Trauma Patients. Mediators of inflammation 2016 (2016)