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Early expression onset of tissue-specific effector genes during the specification process in sea urchin embryos.

Shumpei YamakawaAtsuko YamazakiYoshiaki MorinoHiroshi Wada
Published in: EvoDevo (2023)
Based on this finding, we propose that the expression onset of tissue-specific effector genes is controlled more dynamically than suggested in the previously proposed simplistic regulation scheme. Thus, we suggest that differentiation should be conceptualized as a seamless process of accumulation of effector expression along with the advancing specification GRN. This pattern of effector gene expression may have interesting implications for the evolution of novel cell types.
Keyphrases
  • poor prognosis
  • gene expression
  • regulatory t cells
  • dendritic cells
  • type iii
  • genome wide
  • dna methylation
  • bone marrow
  • single cell
  • mesenchymal stem cells
  • bioinformatics analysis
  • stem cells
  • immune response