Supraperiosteal technique protocol for forehead filling with a mixture of calcium hydroxyapatite and hyaluronic acid: Double-blind, randomized controlled clinical trial.

Natália ScarduaDenize Peruzzo RovarisKelly Maria Silva MoreiraAndre Luiz Sena GuimaraesMaria Tereza Scardua

Published in: Journal of cosmetic dermatology (2024)

The supraperiosteal application of CaHA and HA for forehead treatment demonstrates superior efficacy in addressing signs of aging compared to the isolated use of CaHA.

Keyphrases

hyaluronic acid
botulinum toxin
double blind
randomized controlled trial
clinical trial
study protocol
combination therapy
phase iii
bone regeneration
tissue engineering
replacement therapy