Claudin-1 and Claudin-3 as Molecular Regulators of Myelination in Leukoaraiosis Patients.

Yan Chen Zheng Zheng Ainong Mei Huan Huang Fan Lin

Published in: Clinics (Sao Paulo, Brazil) (2021)

Our data has demonstrated that the abnormal expression of claudin-1 and claudin-3 regulates the pathological progression of leukoaraiosis by governing the viability and myelination of oligodendrocytes. These findings provide novel insights into the regulatory mechanisms underlying the roles of claudin-1 and claudin-3 in leukoaraiosis.

Keyphrases

end stage renal disease
transcription factor
ejection fraction
newly diagnosed
poor prognosis
prognostic factors
peritoneal dialysis
electronic health record
big data
binding protein
single molecule
machine learning
long non coding rna
patient reported outcomes
deep learning
data analysis