Gut Microbiome-Dependent Metabolic Pathways and Risk of Lethal Prostate Cancer: Prospective Analysis of a PLCO Cancer Screening Trial Cohort.

Chad A ReichardBryan D Naelitz Zeneng WangXun JiaJianbo LiMeir J StampferEric E KleinStanley L HazenNima Sharifi

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2021)

Dietary composition, circulating metabolite levels, and downstream signaling pathways may represent modifiable risk factors associated with incident lethal prostate cancer. Beta-adrenergic blockade represents an additional target for oncologic risk reduction.

Keyphrases

prostate cancer
radical prostatectomy
papillary thyroid
signaling pathway
cardiovascular disease
clinical trial
study protocol
squamous cell
randomized controlled trial
phase ii
rectal cancer
squamous cell carcinoma
type diabetes
robot assisted
young adults