Adverse cardiac mechanics and incident coronary heart disease in the Cardiovascular Health Study.

Daniele MasseraMo HuJoseph A DelaneyTraci M BartzMegan E BachStephen J DvorakChristopher R DeFilippiBruce M PsatyJohn S GottdienerJorge R KizerSanjiv J Shah

Published in: Heart (British Cardiac Society) (2021)

We found an association between echocardiographic measures of subclinically altered LV mechanics and incident CHD. These findings inform the underlying biology of subclinical LV dysfunction and CHD. Early detection of asymptomatic myocardial dysfunction may offer an opportunity for prevention and early intervention.

Keyphrases

left ventricular
cardiovascular disease
oxidative stress
randomized controlled trial
mitral valve
pulmonary hypertension
heart failure
emergency department
atrial fibrillation