Aberrant epigenetic alteration of PAX1 expression contributes to parathyroid tumorigenesis.

Priyanka SinghSanjay Kumar BhadadaAshutosh Kumar AryaUma Nahar SaikiaNaresh SachdevaDivya DahiyaJyotdeep KaurMaria Luisa BrandiSudhaker Dhanwada Rao

Published in: The Journal of clinical endocrinology and metabolism (2021)

Our study not only reveals expression of PAX1 is epigenetically deregulated but also paves a way for clinical and therapeutic implications in patients with PHPT.

Keyphrases

poor prognosis
gene expression
dna methylation
long non coding rna