Radiotherapy with or without chemotherapy for locally advanced head and neck cancer in elderly patients: analysis of the Head and Neck Cancer Registry of Japan.

Koichi YasudaYusuke UchinamiSatoshi KanoJun TaguchiDaisuke KawakitaMegumi KitayamaKentaro NishiokaTakashi MoriFuki KoizumiYuri FujiiYasushi ShimizuKeiji KobashiSeiichi YoshimotoKen-Ichi NibuAkihiro HommaHidefumi Aoyama

Published in: International journal of clinical oncology (2023)

Although aggressive CRT is administered to elderly patients in Japan, its effectiveness is uncertain. Further prospective randomized trials are needed to verify whether CRT is superior to RT alone for elderly patients.

Keyphrases

locally advanced
randomized controlled trial
cardiac resynchronization therapy
early stage
systematic review
radiation therapy
heart failure
radiation induced
squamous cell carcinoma
rectal cancer