Long-term observational studies with cannabis-based medicines for chronic non-cancer pain: A systematic review and meta-analysis of effectiveness and safety.
Patric BialasMary-Ann FitzcharlesPetra KloseWinfried HäuserPublished in: European journal of pain (London, England) (2022)
There is very low quality evidence for the long-term effectiveness (pain, sleep, mood, health-related quality of life), tolerability and safety of medical cannabis for chronic non-cancer pain (CNCP) according to reports of prospective observational studies. Predefined criteria of a large magnitude of effect size in these types of studies were not met. Nevertheless, long-term medical cannabis therapy can be considered in some carefully selected and monitored patients with CNCP.
Keyphrases
- chronic pain
- papillary thyroid
- pain management
- neuropathic pain
- healthcare
- squamous cell
- randomized controlled trial
- systematic review
- sleep quality
- bipolar disorder
- emergency department
- squamous cell carcinoma
- stem cells
- open label
- lymph node metastasis
- tyrosine kinase
- depressive symptoms
- spinal cord
- cell therapy
- case control
- replacement therapy