The transition between acute and chronic infections in light of energy control: a mathematical model of energy flow in response to infection.
Gang ZhaoRainer H StraubMichael Meyer HermannPublished in: Journal of the Royal Society, Interface (2022)
These results suggest a fundamental role for brain and fat in controlling immune response through systemic energy control. In particular, it suggests that lipolysis resistance, which is known to be involved in obesity and ageing, might be a survival programme for coping with chronic infections.
Keyphrases
- immune response
- adipose tissue
- drug induced
- insulin resistance
- liver failure
- metabolic syndrome
- weight loss
- depressive symptoms
- resting state
- randomized controlled trial
- multiple sclerosis
- toll like receptor
- physical activity
- intensive care unit
- functional connectivity
- body mass index
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome