Enhanced active case finding of drug-resistant tuberculosis in Namibia: a protocol for the hotspots, hospitals, and households (H3TB) study.
Olga ShavukaEtuhole IipumbuLorraine BooisGunar GüntherGraeme HoddinottHsien-Ho LinEmmanuel NepoloStefan NiemannNunurai RuswaJames SeddonMareli M ClaassensPublished in: BMJ open (2024)
Ethics approval was obtained. Participants will give informed consent. H3TB will capitalise on a partnership with the Ministry of Health and Social Services to follow up individuals diagnosed with MDR-TB and integrate WGS data with innovative contact network mapping, to allow enhanced case finding. Study data will contribute towards a systems approach to TB control. Equally important, it will serve as a role model for similar studies in other high-incidence settings.
Keyphrases
- emergency department
- drug resistant
- mycobacterium tuberculosis
- healthcare
- multidrug resistant
- public health
- mental health
- big data
- electronic health record
- randomized controlled trial
- acinetobacter baumannii
- machine learning
- pulmonary tuberculosis
- risk factors
- artificial intelligence
- cystic fibrosis
- deep learning
- hiv infected
- pseudomonas aeruginosa
- affordable care act