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MiR-223-3p and miR-22-3p inhibit monosodium urate-induced gouty inflammation by targeting NLRP3.

Xiang WangJingwei ChiBingzi DongLili XuYue ZhouYajing HuangShengnan SunFanxiang WeiYuzhao LiuChuanfeng LiuKui CheWenshan LvYing ChenYangang Wang
Published in: International journal of rheumatic diseases (2021)
The findings of the present study show that miR-223-3p and miR-22-3p can reduce the inflammatory effects of gout by inhibiting the expression of NLRP3.
Keyphrases
  • oxidative stress
  • poor prognosis
  • diabetic rats
  • high glucose
  • signaling pathway
  • uric acid
  • binding protein
  • endothelial cells