Cellular and Molecular Mechanisms of Kidney Injury in 2,8-Dihydroxyadenine Nephropathy.
Barbara Mara KlinkhammerSonja DjudjajUta KunterRunolfur PalssonVidar Orn EdvardssonThorsten WiechMargret ThorsteinsdottirSverrir HardarsonOrestes Foresto-NetoShrikant R MulayMarcus Johannes MoellerWilhelm Jahnen-DechentJürgen FloegeHans-Johachim AndersPeter BoorPublished in: Journal of the American Society of Nephrology : JASN (2020)
Rodent models of the cellular and molecular mechanisms of 2,8-DHA nephropathy and crystal clearance have clinical relevance and offer insight into potential future targets for therapeutic interventions.