Effect of the machine learning-derived Hypotension Prediction Index (HPI) combined with diagnostic guidance versus standard care on depth and duration of intraoperative and postoperative hypotension in elective cardiac surgery patients: HYPE-2 - study protocol of a randomised clinical trial.
Santino R RellumJaap SchuurmansJimmy SchenkBjörn J P van der SterWard H van der VenBart F GeertsMarkus W HollmannThomas G V CherpanathWim K LagrandPaul WynandtsFrederique PaulusAntoine H G DriessenLotte E TerwindtSusanne EberlHenning HermannsDenise P VeeloAlexander P J VlaarPublished in: BMJ open (2023)
The Netherlands Trial Register (NL9449), ClinicalTrials.gov (NCT05821647).
Keyphrases
- clinical trial
- study protocol
- open label
- machine learning
- patients undergoing
- cardiac surgery
- randomized controlled trial
- end stage renal disease
- phase ii
- phase iii
- double blind
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- acute kidney injury
- peritoneal dialysis
- quality improvement
- artificial intelligence
- pain management
- health insurance