Epithelioid angiosarcoma of the pericardium: Case report of the challenges in the management of a rare malignancy with poor prognosis.
Bhupesh GuleriaPrerna GuleriaAzhar HusainAnurag JainJes RaphaelPrasanta SenguptaPublished in: Indian journal of cancer (2024)
A primary epithelioid angiosarcoma of the pericardium is a rare soft tissue malignancy. This report describes a young adult woman who presented with progressive dyspnea and pericardial effusion. She was found to have pericardial mass on imaging along with extensive myocardial infiltration. The biopsy of the mass revealed epithelioid angiosarcoma, which was CD34 and CD31-immuno-positive. Due to unresectable disease, she was given a trial of immunotherapy followed by conventional chemotherapy. She showed partial response on interim assessment, but progressed soon after the completion of six cycles and succumbed to her rapidly progressive illness within nine months of diagnosis. This report discusses the diagnostic and therapeutic challenges faced while managing this disease of aggressive tumor biology.
Keyphrases
- poor prognosis
- case report
- long non coding rna
- multiple sclerosis
- young adults
- soft tissue
- locally advanced
- clinical trial
- study protocol
- squamous cell carcinoma
- left ventricular
- heart failure
- nk cells
- phase ii
- photodynamic therapy
- rectal cancer
- fluorescence imaging
- childhood cancer
- clinical evaluation
- chemotherapy induced