Fixed-Dose Combination Therapy for Prevention of Cardiovascular Diseases in CKD: An Individual Participant Data Meta-analysis.
Sadaf G SepanlouJohannes F E MannPhilip JosephPrem PaisPeggy GaoMaryam SharafkhahGholamreza RoshandelSalim YusufReza MalekzadehPublished in: Clinical journal of the American Society of Nephrology : CJASN (2023)
A fixed-dose combination treatment strategy is effective and safe at preventing cardiovascular disease, irrespective of eGFR but relative and absolute risk reductions are larger in individuals with low eGFR.
Keyphrases
- combination therapy
- cardiovascular disease
- small cell lung cancer
- systematic review
- epidermal growth factor receptor
- tyrosine kinase
- chronic kidney disease
- type diabetes
- meta analyses
- cardiovascular risk factors
- electronic health record
- metabolic syndrome
- randomized controlled trial
- coronary artery disease
- machine learning
- artificial intelligence