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Differentiation of Human Embryonic Stem Cells to Sympathetic Neurons: A Potential Model for Understanding Neuroblastoma Pathogenesis.

Jane Carr-WilkinsonNilendran PrathalingamDeepali PalMohammad MoadNatalie LeeAishwarya SundareshHelen ForghamPeter JamesMary HerbertMajlinda LakoDeborah A Tweddle
Published in: Stem cells international (2018)
We have optimised a method for noradrenergic SNS development using the H9 hESC line to improve our understanding of normal human SNS development and, in a future work, the pathogenesis of neuroblastoma.
Keyphrases
  • endothelial cells
  • embryonic stem cells
  • induced pluripotent stem cells
  • pluripotent stem cells
  • spinal cord
  • spinal cord injury