The interplay between tamoxifen and endoxifen plasma concentrations and coagulation parameters in patients with primary breast cancer.
Sanne M BuijsDaan C H van DorstMarieke J H A KruipRob F P van den AkkerKa L CheungRobert PorrazzoEsther Oomen-de HoopAgnes JagerStijn L W KoolenJorie VersmissenA H Jan DanserHenri H VersteegMettine H A BosRon H J MathijssenPublished in: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2023)
Our results indicate that higher tamoxifen and endoxifen levels are not correlated with an increased procoagulant state, suggesting tamoxifen dose escalation does not further promote hypercoagulability.