Virological Characterization of the First 2 COVID-19 Patients Diagnosed in Italy: Phylogenetic Analysis, Virus Shedding Profile From Different Body Sites, and Antibody Response Kinetics.

Francesca ColavitaDaniele LapaFabrizio CarlettiEleonora LalleFrancesco MessinaMartina RuecaGiulia MatusaliSilvia MeschiLicia BordiPatrizia MarsellaEmanuele NicastriLuisa MarchioniAndrea MarianoLaura ScorzoliniTommaso Ascoli BartoliAntonino di CaroGiuseppe IppolitoMaria Rosaria CapobianchiConcetta Castillettinull null

Published in: Open forum infectious diseases (2020)

Our longitudinal analysis showed that SARS-CoV-2 RNA can be detected in different body samples, which may be associated with broad tropism and different spectra of clinical manifestations and modes of transmission. Profiling antibody response and neutralizing activity can assist in laboratory diagnosis and surveillance actions.

Keyphrases

sars cov
public health
hiv infected
single cell
cross sectional
antiretroviral therapy
dengue virus
nucleic acid