Efficacy of ketamine mouthwash in the management of oral and pharyngeal toxicity associated with head and neck chemoradiotherapy: protocol for a phase II, Simon's two-stage trial.

Daniel M KofflerJacob EcksteinJoseph HermanDiana Martins-WelchNagashree SeetharamuMaged GhalyNina KohnLouis PottersDouglas FrankKevin SullivanBhupesh Parashar

Published in: BMJ open (2023)

NCT05331131.

Keyphrases

phase ii
clinical trial
open label
phase iii
rectal cancer
placebo controlled
randomized controlled trial
locally advanced
oxidative stress
double blind
pain management
study protocol
squamous cell carcinoma
oxide nanoparticles
chronic pain