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Systemic inflammatory response syndrome after transcatheter or surgical aortic valve replacement.

Brian R LindmanJacob S GoldsteinMichael E NassifAlan ZajariasEric NovakAnjan TibrewalaAnna M VatterottCassandra LawlerRalph J DamianoMarc R MoonJennifer S LawtonJohn M LasalaHersh S Maniar
Published in: Heart (British Cardiac Society) (2015)
Severe SIRS was associated with a higher mortality after SAVR or TAVR. It occurred more commonly after SAVR and had a greater effect on mortality in diabetic patients. These findings may have implications for treatment decisions in patients with AS, may help explain differences in outcomes between different AVR approaches and identify diabetic patients as a high-risk subgroup to target in clinical trials with therapies to attenuate SIRS.
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