Understanding the impact of non-shared unmeasured confounding on the sibling comparison analysis.

Buket Öztürk Esen Vera Ehrenstein Irene Petersen Henrik Toft Sorensen Lars Pedersen

Published in: International journal of epidemiology (2024)

Researchers should be aware of the challenge regarding non-shared unmeasured confounding in the sibling comparison analysis, before applying the analysis in non-randomized studies. Otherwise, the sibling comparison analysis may lead to substantial bias.

Keyphrases

randomized controlled trial
open label
double blind
case control