Evaluation of cell survival in different 3D-printed geometric shapes of human iPSC-derived engineered heart tissue.

Yalin YildirimLouisa DegenerLukas ReuterJohannes PetersenLilian GabelAnnika SommerChristiane PahrmannHermann ReichenspurnerSimon Pecha

Published in: Artificial organs (2024)

Use of 3D-printing allows the creation of EHTs in all desired geometric shapes. The geometry with an optimized surface-area-to-volume-ratio (ring EHT) demonstrated a significantly higher cell survival measured by RT-PCR, Bioluminescence imaging, and cytometric studies using FACS analysis.

Keyphrases

induced pluripotent stem cells
endothelial cells
high resolution
heart failure
atrial fibrillation
pluripotent stem cells
energy transfer
mass spectrometry
real time pcr