The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal-fetal transmission: a systematic review and meta-analysis.
Kuma DiribaEphrem AwulachewEyob GetuPublished in: European journal of medical research (2020)
Coronavirus infection is more likely to affect pregnant women. Respiratory infectious diseases have demonstrated an increased risk of adverse maternal obstetrical complications than the general population due to physiological changes occurred during pregnancy. None of the studies reported transmission of CoV from the mother to the fetus in utero, which may be due to a very low expression of angiotensin-converting enzyme-2 in early maternal-fetal interface cells.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- pregnancy outcomes
- pregnant women
- angiotensin converting enzyme
- infectious diseases
- birth weight
- angiotensin ii
- induced apoptosis
- poor prognosis
- risk factors
- emergency department
- cell proliferation
- signaling pathway
- physical activity
- endoplasmic reticulum stress
- adverse drug
- pi k akt