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SARS-CoV-2: An Updated Review Highlighting Its Evolution and Treatments.

Xirui ZhangHao YuanZipeng YangXiaoyu HuYasser S MahmmodXiaojing ZhuCuiping ZhaoJingbo ZhaiXiu-Xiang ZhangShengjun LuoXiao-Hu WangMengzhou XueChunfu ZhengZi-Guo Yuan
Published in: Vaccines (2022)
Since the SARS-CoV-2 outbreak, pharmaceutical companies and researchers worldwide have worked hard to develop vaccines and drugs to end the SARS-CoV-2 pandemic. The potential pathogen responsible for Coronavirus Disease 2019 (COVID-19), SARS-CoV-2, belongs to a novel lineage of beta coronaviruses in the subgenus arbovirus. Antiviral drugs, convalescent plasma, monoclonal antibodies, and vaccines are effective treatments for SARS-CoV-2 and are beneficial in preventing infection. Numerous studies have already been conducted using the genome sequence of SARS-CoV-2 in comparison with that of other SARS-like viruses, and numerous treatments/prevention measures are currently undergoing or have already undergone clinical trials. We summarize these studies in depth in the hopes of highlighting some key details that will help us to better understand the viral origin, epidemiology, and treatments of the virus.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • coronavirus disease
  • clinical trial
  • randomized controlled trial
  • risk factors
  • risk assessment
  • single cell
  • optical coherence tomography
  • climate change
  • drug induced