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Calcitriol increases MBNL1 expression and alleviates myotonic dystrophy phenotypes in HSA LR mouse models.

Kun HuangDan-Dan WangWen-Bao HuWei-Qian ZengXia XuQiu-Xiang LiFang-Fang BiHuan YangJian Qiu
Published in: Journal of translational medicine (2022)
Our study suggests that calcitriol is a potential pharmacological strategy for DM1 that enhances MBNL1 expression.
Keyphrases
  • poor prognosis
  • mouse model
  • binding protein
  • long non coding rna
  • early onset
  • metabolic syndrome
  • duchenne muscular dystrophy