Persistent expression of activation markers on Mycobacterium tuberculosis-specific CD4 T cells in smear negative TB patients.

Ahmed EsmaelAdane MihretTamrat AbebeDaniel MussaSebsibe NewayJoel ErnstJyothi RengarajanLiya WassieRawleigh Howe

Published in: PloS one (2022)

After six months of standard anti-TB therapy, persistent levels of activation of HLA-DR and CD-38 from PPD specific CD4+T cells in this study could indicate that those markers have little value in monitoring and predicting anti-TB treatment response in smear negative pulmonary TB patients in Ethiopian context.

Keyphrases

mycobacterium tuberculosis
end stage renal disease
ejection fraction
pulmonary tuberculosis
newly diagnosed
chronic kidney disease
prognostic factors
poor prognosis
pulmonary hypertension
cell therapy