Persistent expression of activation markers on Mycobacterium tuberculosis-specific CD4 T cells in smear negative TB patients.
Ahmed EsmaelAdane MihretTamrat AbebeDaniel MussaSebsibe NewayJoel ErnstJyothi RengarajanLiya WassieRawleigh HowePublished in: PloS one (2022)
After six months of standard anti-TB therapy, persistent levels of activation of HLA-DR and CD-38 from PPD specific CD4+T cells in this study could indicate that those markers have little value in monitoring and predicting anti-TB treatment response in smear negative pulmonary TB patients in Ethiopian context.