Molecular mechanism of FSHR expression induced by BMP15 in human granulosa cells.
Ken ShimizuTomoko Nakamuranull BayasulaNatsuki NakanishiYukiyo KasaharaTakashi NagaiTomohiko MuraseSatoko OsukaMaki GotoAkira IwaseFumitaka KikkawaPublished in: Journal of assisted reproduction and genetics (2019)
BMP15 induced FSHR expression in human granulosa cells through Smad and non-Smad pathways. This mechanism of FSHR induction by BMP15 may be utilized for controlling follicular growth.
Keyphrases
- induced apoptosis
- endothelial cells
- poor prognosis
- mesenchymal stem cells
- cell cycle arrest
- epithelial mesenchymal transition
- induced pluripotent stem cells
- transforming growth factor
- high glucose
- endoplasmic reticulum stress
- polycystic ovary syndrome
- bone regeneration
- oxidative stress
- signaling pathway
- adipose tissue
- long non coding rna
- diabetic rats
- insulin resistance
- stress induced