LncRNA 51325 Alleviates Bone Cancer Induced Hyperalgesia Through Inhibition of Pum2.

Yahui WangChengfei XuPeng LiuQiuli HeShihua ZhangZhihao LiuChaobo NiLiping ChenTong ZhiLongsheng XuLiang ChengXuewu LinMing YaoHuadong Ni

Published in: Journal of pain research (2024)

Our findings indicate that lncRNA51325 plays a role in regulating bone cancer pain by inhibiting Pum2 expression, offering a promising avenue for novel treatments targeting nociceptive hypersensitivity induced by bone metastatic cancer.

Keyphrases

papillary thyroid
squamous cell
bone mineral density
neuropathic pain
squamous cell carcinoma
poor prognosis
chronic pain
long non coding rna
soft tissue
signaling pathway
bone loss
pain management
spinal cord injury
cancer therapy
young adults
high glucose