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Men and women respond differently to rapid weight loss: Metabolic outcomes of a multi-centre intervention study after a low-energy diet in 2500 overweight, individuals with pre-diabetes (PREVIEW).

Pia Siig VestentoftThomas Meinert LarsenMargriet Westerterp-PlantengaIan MacdonaldJosé Alfredo Martínez HernándezSvetoslav HandjievSally PoppittSylvia HansenChristian RitzArne AstrupLaura Pastor-SanzFinn Sandø-PedersenKirsi H PietiläinenJouko SundvallMathjis DrummenMoira A TaylorSantiago Navas-CarreteroTeodora Handjieva-DarlenskaShannon BrodieMarta P SilvestreMaija Huttunen-LenzJennie Brand-MillerMikael FogelholmAnne Raben
Published in: Diabetes, obesity & metabolism (2018)
An 8-week LED induced different effects in women than in men. These findings are clinically important and suggest gender-specific changes after weight loss. It is important to investigate whether the greater decreases in FFM, hip circumference and HDL cholesterol in women after rapid weight loss compromise weight loss maintenance and future cardiovascular health.
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