Balancing Statistical Power and Risk in HIV Cure Clinical Trial Design.

Jillian S Y LauDeborah CromerMykola PinkevychSharon R LewinThomas A RasmussenJames H McMahonMiles P Davenport

Published in: The Journal of infectious diseases (2022)

Current TVR HIV cure studies are underpowered to detect statistically significant changes in frequency of viral reactivation. Alternate study designs can improve the statistical power of ATI trials.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
hiv testing
clinical trial
human immunodeficiency virus
hepatitis c virus
hiv aids
men who have sex with men
sars cov
south africa
study protocol
randomized controlled trial
double blind