Investigating VEGF. miR-145-3p, and miR-101-3p Expression in Patients with Cholangiocarcinoma.
Maria Clara Jessica CalastriRafael Fernandes FerreiraGraciele Domitila TenaniLucas Poleto SpinolaGabriel Feltrin VieiraMaria Filomena Rabaça Roque BotelhoAna Margarida Coelho AbrantesJosé Guilherme Lopes Rodrigues TralhãoAna Filipa Marques De BritoRenato Ferreira Da SilvaRita de Cássia Martins Alves da SilvaEliane Milharcix ZanoveloLarissa Bastos Eloy Da CostaDaniele Caroline Brito De SouzaDalisio De Santi NetoIlka de Fátima Ferreira Santana BoinDoroteia Rossi Silva SouzaPublished in: Asian Pacific journal of cancer prevention : APJCP (2022)
The underexpression of miRNAs, tumor suppressors, the overexpression of VEGF, smoking, and aging were associated with CCA based on our findings. It seems that the reduced expression of the studies miRNAs and increased expression of VEGF can contribute to a decrease in survival rate of patients with tumor in their intrahepatic bile ducts.