Changes in QTc interval after hydroxychloroquine therapy in patients with COVID-19 infection: a large, retrospective, multicentre cohort study.

Moutaz El KadriOmar Al FalasiRizwan AhmedAhlam Al AwadhiZainab AltahaAmany HillisBasheer PanikkaveetilSara AbdallaHoney Ansel BenetteAdhba AlmubarakMohammed SaifuddinYousef AlattarAbderrahim OulhajSalem AlKaabi

Published in: BMJ open (2022)

The incidence of severe QTc prolongation with hydroxychloroquine was low and not associated with ventricular arrhythmia. The safety concerns surrounding the use of hydroxychloroquine may have been overestimated; however, caution should be exercised when using hydroxychloroquine in patients with risk factors for QT prolongation.

Keyphrases

drug induced
cross sectional
heart failure
left ventricular
early onset
stem cells
study protocol
cell therapy