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Impact of Bone Morphogenetic Protein 7 and Prostaglandin receptors on osteoblast healing and organization of collagen.

Mohammad Ali SalamaAsmaa Anwar IsmailMd Sofiqul IslamAghila Rani K GSausan Al KawasA B Rani SamsudinSmriti Aryal A C
Published in: PloS one (2024)
The combination of a Prostaglandin EP2 receptor agonist or an EP1 receptor antagonist when combined with low dose BMP7 significantly hinders both human osteoblast healing and collagen maturity/concentration in comparison to low dose BMP7 treatment alone.
Keyphrases
  • low dose
  • bone regeneration
  • high dose
  • mesenchymal stem cells
  • endothelial cells
  • tissue engineering
  • induced pluripotent stem cells
  • pluripotent stem cells
  • combination therapy
  • replacement therapy
  • smoking cessation