Impact of Bone Morphogenetic Protein 7 and Prostaglandin receptors on osteoblast healing and organization of collagen.

Mohammad Ali SalamaAsmaa Anwar IsmailMd Sofiqul IslamAghila Rani K GSausan Al KawasA B Rani Samsudin Smriti Aryal A C

Published in: PloS one (2024)

The combination of a Prostaglandin EP2 receptor agonist or an EP1 receptor antagonist when combined with low dose BMP7 significantly hinders both human osteoblast healing and collagen maturity/concentration in comparison to low dose BMP7 treatment alone.

Keyphrases

low dose
bone regeneration
high dose
mesenchymal stem cells
endothelial cells
tissue engineering
induced pluripotent stem cells
pluripotent stem cells
combination therapy
replacement therapy
smoking cessation