A Retrospective Comparison of the Effectiveness and Safety of Intravenous Olanzapine Versus Intravenous Haloperidol for Agitation in Adult Intensive Care Unit Patients.

Michelle WangTuyen T YankamaGeorge T AbdallahIjeoma Julie EcheKristen N KnophAdrian WongParth PatelDouglas HsuIfeoma Mary Eche

Published in: Journal of intensive care medicine (2021)

In this retrospective cohort study, there was no difference in the effectiveness of IV olanzapine compared to IV haloperidol for the management of agitation. IV olanzapine was associated with an increased incidence of bradycardia and somnolence.

Keyphrases

intensive care unit
end stage renal disease
high dose
newly diagnosed
ejection fraction
chronic kidney disease
randomized controlled trial
systematic review
chemotherapy induced
peritoneal dialysis
risk factors
prognostic factors
low dose
mechanical ventilation
patient reported outcomes