Smad7 positively regulates keratinocyte proliferation in psoriasis.

D Di FuscoF LaudisiV DinalloI MonteleoneA Di GraziaI MarafiniE TronconeA ColantoniA OrtenziC StolfiM PicardoGiovanni Monteleone

Published in: The British journal of dermatology (2017)

Our data show that Smad7 is overexpressed in human and murine psoriasis and suggest a key role of this molecule in the control of keratinocyte proliferation.

Keyphrases

epithelial mesenchymal transition
signaling pathway
transforming growth factor
endothelial cells
electronic health record
atopic dermatitis
big data
pluripotent stem cells
data analysis